In addition, sometimes manufacturers use a dot system, with one dot usually representing the lowest nicotine level and four or five dots usually being the highest level among the range of products available in a brands portfolio
doi:10.11606/t.8.2008.tde-01122009-093954
D., Anvari, S., Lee, Y., Samaan, Z., Banfield, L., Thabane, L., & Samaan, M
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(1992) studied in guinea-pigs the effects of combined exposure and single exposure to ozone and cigarette smoke on airway responsiveness and tracheal vascular permeability and found that the combined exposure increased airway responsiveness and vascular permeability to a greater extent in terms of magnitude, but not in duration, than a single exposure