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Pharma companies are downsizing and some of them have closed their neuropsychiatric divisions because right now it is difficult to do that type of research and it is not economically profitable for pharmaceutical companies. Simon Chapman, professor of public health at the University of Sydney, takes a dim view of the medicalization of quitting

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Effect estimates from each study were extracted and combined together using the random-effect, generic inverse variance method of DerSimonian and Laird

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