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Cytisinicline was associated with a greater rate of nicotine-containing e-cigarette cessation compared with placebo during 12 weeks of treatment and up to 4 weeks posttreatment, according to results from the phase 2 ORCA-VI trial
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Multiple studies clearly show that DAA-based therapy in persons with past or current injection drug use results in high SVR rates, comparable to those seen in persons who do not use drugs.[21,24] Elbasvir-Grazoprevir (C-EDGE CO-STAR) : In this phase 3 multinational study (C-EDGE CO-STAR), investigators evaluated HCV treatment with elbasvir-grazoprevir in 301 PWID who had also been receiving opioid agonist therapy (e.g