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Cui LH, Shin MH, Kweon SS, Kim HN, Song HR, Piao JM, Choi JS, Shim HJ, Hwang JE, Kim HR, et al

Y-H differentiation as an antifungal target Besides targeting the cell membrane and associated components of fungi, given the importance of the Y-H phenotypic switch in fungal virulence, targeting this transition can be a promising antifungal therapy

78 HP 160 CAGRILINTIDE Long-Acting Amylin Analog ALIASES Cagrilintide, AM833, long-acting amylin analog CLASS Synthetic amylin analog once-weekly dual amylin/calcitonin agonist FORMULA CHNO (approx) SEQUENCE 37-residue amylin analog with C20-fatty-acid albumin tether HALF-LIFE ~7 days (once-weekly dosing) ROUTES Subcutaneous (Phase 2/3 clinical) MECHANISM OF ACTION Long-acting amylin analog

443 Lipids that accumulate during regeneration not only serve as the energy supply and substrates for membrane synthesis but also directly contribute to regulating the downstream production of metabolites to coordinate cell proliferation via transcriptional or epigenetic mechanisms

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