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Its unusual stability in acidic environments (pH 12 gastric fluid) has been documented, though the structural basis for this resistance is not fully characterized

In contrast, methionine exhibited a formulation-dependent response, with significantly higher dose-normalized exposure and peak response after LipoMicel compared with the standard formulation

Allison JJ

In life, this can result from excessive or repetitive mechanical loading 20,21 , and discs are intrinsically most vulnerable to herniation in middle-age, following moderate (but not severe) degenerative changes 6,22

Both S100- and GFAP-positive areas were significantly increased compared to healthy controls (Fig