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Some investigators have proposed that GLP-1RAs improve myocardial insulin sensitivity, enhance glucose oxidation rates, reduce fatty acid oxidation, and thereby optimize myocardial energy metabolism, ultimately improving cardiac function.106 In a randomized controlled trial (RCT) conducted by Mikhail et al,106 semaglutide efficacy was evaluated in 616 patients with obesity-related heart failure and T2DM

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Coenzyme Q10 attenuates human platelet aggregation induced by SARS-CoV-2 spike protein via reducing oxidative stress in vitro

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The clinical significance is generally modest, but caution is warranted for medicines with a narrow therapeutic index