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Epidemiological studies have shown associations between elevated endogenous IGF-1 levels and increased risk of certain cancers, including prostate, breast, and colorectal cancers

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It defined individual distinct RCD modalities, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death, entotic cell death, ferroptosis, lysosome-dependent cell death, mitochondrial permeability transition-driven necrosis, mitotic death, necroptosis, NETotic cell death, parthanatos, and pyroptosis [4]

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