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Table 4 Results of a 26-week Trial of Liraglutide Injection as Add-on to Metformin in Adults with Type 2 Diabetes Mellitus a Liraglutide Injection Compared to Sitagliptin, Both as Add-on to Metformin In this 26-week, open-label trial, 665 adult patients with type 2 diabetes mellitus on a background of metformin 1,500 mg per day were randomized to liraglutide injection 1.2 mg once daily, liraglutide injection 1.8 mg once daily or sitagliptin 100 mg once daily, all dosed according to approved labeling

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A pattern driven by circadian suppression of MDM2 transcription during the morning window