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Vitamin B12 and iron are needed for healthy blood cell function, and deficiencies can lead to anemia, a condition characterized by ineffective transport of oxygen to cells and tissues

Stress increases permeability and bacterial translocation linked to MAPK p38/Nrf2 pathways [107,108]

Energy restriction requires coordinated metabolic reorganization involving hepatic glucose output, adipose tissue lipolysis, skeletal muscle protein turnover, and mitochondrial fuel selection

and non-stimulant medications such as atomoxetine, guanfacine and clonidine), intake of these medications are commonly associated with adverse effects ranging from loss of appetite, and irritability to suicidal ideation 18,19 and therefore are not well-tolerated 20