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Acne vulgaris is not listed as a recognised adverse effect in the MHRA-approved product information for semaglutide

Particularly notable is the increased occurrence rate among this age group in conditions such as starvation ketosis acidosis, sensory abnormalities, and medullary thyroid carcinoma

1 Weight loss has also been correlated with changes in thyroid levels

Tissue hypoxia and oxidative stress also can contribute to non-immune mediated tissue injury driven by renal stromal cells, further enhancing interstitial immune cell infiltration and fibrosis to create a viscous cycle3

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