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Standard GI research endpoints include: macroscopic damage scoring (CDAI-equivalent scales in IBD models), histological assessment (H&E staining, villus/crypt morphometry), tight junction protein expression (Western blot, immunofluorescence), permeability assays (FITC-dextran, Ussing chambers), and inflammatory cytokine panels

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Researchers believe this reduction may partly contribute to slower healing, collagen loss, inflammation, tissue degeneration, and visible signs of aging

Notes: A single 100mg epithalon course under the Russian Protocol requires two 50mg epithalon vials