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Willingness to Commit to Lifestyle Changes: Semaglutide is most effective when combined with lifestyle modifications, including a reduced-calorie diet and increased physical activity

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"GLP-1s can be life-changing for patients managing obesity and related conditions," Chris Klomp, director of Medicare and chief counselor at the U.S

For example, individuals with specific FTO and MC4R variants may experience different appetite suppression patterns, potentially making keto less necessary or better tolerated