After writing dozens of GLP-1 articles over the past year, one issue that consistently comes up is the affordability of popular medications like Ozempic, Wegovy and Zepbound for weight loss
Joshua Silva, MD Nov 7, 2025 13 min read Updated: Apr 17 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As GLP-1 and GLP-1/GIP medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) continue to transform medical weight management, one question comes up repeatedly: Do these medications cause muscle lossor even muscle wasting
Gastrointestinal issues such as nausea and vomiting remain the most common side effects
Most menstrual irregularities associated with weight loss are temporary and resolve as the body adjusts to metabolic changes
These are newer medications, so we dont have long-term outcome studies, especially in young people and pediatric patients, Michelle Van Name, MD, an assistant professor in pediatric endocrinology and diabetes at Yale School of Medicine, told Teen Vogue