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developed a shikonin-loaded PLGA nanoparticle hydrogel (size not specified) that significantly downregulated p65 and p-p65 expression and reduced IL-17A, IL-17F, IL-22, IL-1, and TNF- levels in HaCaT cells and IMQ-induced mice

Zinc Supports the maintenance of normal skin, hair and nails

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Its chemical structure involves a betaine configuration with a sulfur atom attached to the imidazole ring, and thiol and thione forms exist as a tautomer (Fig